Notch Signaling pathway

Construction and identification of a reporter plasmid for analyses of Notch signaling pathway

细胞内活化的Notch途径报告基因质粒的构建和鉴定

Notch signaling pathway and primary liver cancer

Notch信号转导通路与原发性肝癌

The Notch signaling pathway has very important effect in the process of animal growth , especially in the animal development .

Notch信号通路在动物的生长中具有很重要的作用，尤其是对动物的发育有很深的影响。

Gene Expression Profile of Notch Signaling Pathway and the Metastasis of Adenoid Cystic Carcinoma

Notch信号通路相关基因的表达与涎腺腺样囊性癌转移的关系

Notch signaling pathway is a minority signal transduction systems regulating cell proliferation and apoptosis repeatedly .

Notch信号通路是少数反复调节细胞增殖和凋亡的信号转导系统。

Effects of blocking Notch signaling pathway on the proliferation and senescence of human dental pulp cells

阻断Notch信号通路对人牙髓细胞增殖和老化的影响

Notch Signaling Pathway and Multiple Myeloma & Review

Notch信号通路和多发性骨髓瘤

Bone Marrow Mesenchymal Stem Cells Promote Endogenous Neural Stem Cells Proliferation by Notch Signaling Pathway after Stroke

骨髓间充质干细胞激活Notch信号通路促进脑缺血后内源性神经干细胞增殖的研究

Thus RBP-J is an essential mediator of Notch signaling pathway .

tch信号途径中一个基本介导物。

Notch Signaling Pathway and Its Regulation

Notch信号途径及其调控

Aberrant regulation of Notch signaling pathway always leads to embryonic death due to defective development of vascular networks .

Notch信号通路调控的异常往往由于血管网络发育的缺陷而导致胚胎死亡。

At the same times through the local interaction between cells , Notch signaling pathway influenced the development and formation of blood vessels .

同时Notch信号途径通过局部细胞间的相互作用也对血管的发育和形成构成重要影响。

Objective To construct and identify a reporter plasmid for analyses of the mechanism of Notch signaling pathway in human cervical carcinoma cells .

目的构建并鉴定一种检测细胞内活化的Notch信号途径的报告基因质粒，用于研究该途径在宫颈癌细胞中的作用机制。

In addition , H. pylori infection can activate the Notch signaling pathway , which may be one of the carcinogenic mechanisms .

另外，胃癌高危因素H.pylori感染可激活Notch信号通路，这可能是其致癌机制之一。

To explore the specific mechanisms of Notch signaling pathway involved in the modulation of myocardial I / RI process . [ Methods ] 1 .

探索Notch信号通路对大鼠心肌细胞缺血/再灌注损伤的调节作用的及其具体机制。

Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism regulates boundary formation between cell population , cell proliferation and cell death .

Notch信号通路是细胞间一种保守的具有调节细胞增殖、分化和凋亡能力的信号机制。

However , the role of Notch signaling pathway in other types of cells such as DC , macrophages and NK cells is still not clear .

但Notch信号途径在其他免疫类型细胞诸如DC、巨噬细胞以及NK细胞发育的调控作用尚不十分清楚。

Notch signaling pathway can be activated during dental pulp repair process , this phenomenon reflects a molecular reflection mechanism in the early stage of pulp repair .

Notch信号通路可以在牙髓损伤修复动态过程中激活表达，体现了一种在组织修复过程早期的分子反应机制。

DON at low concentration ( 10ng / ml ) can inhibit Notch signaling pathway , affect the characteristics of mES cells , proliferation and differentiation .

DON在低浓度（10ng/ml）时即可抑制Notch通路，影响mES细胞的特性维持、增殖及分化等，进而影响早期胚胎发育。

The Notch signaling pathway plays a pivotal role in cell fate specification in development by mediating cell-cell interaction and is conserved during evolution from worm through man .

Notch信号途径是在发育过程中通过介导细胞间的相互作用而调控细胞分化方向的重要信号途径，在进化中高度保守。

The Notch signaling pathway is highly conserved in evolution , and plays an important role in a variety of organisms from nematodes to humans , from embryonic development to adulthood .

Notch信号途径在进化中高度保守，从线虫到人，从胚胎发育到成年个体的多种系统中都发挥着重要作用。

Among them , the Notch signaling pathway composed of Notch receptors , transcription factor RBP-J and its downstream effectors , is one of the fundamental regulatory pathways during development .

以细胞膜受体Notch、转录因子RBP-J及其下游效应基因组成的Notch信号途径是调控发育过程的基本信号之一。

Comparative Study on the Viscoelastic Properties of Phagocytes of Atherosclerotic Origin Regulation of the Differentiation and Function of the Bone Marrow Monocyte-derived Dendritic Cells and Macrophages by the Notch Signaling Pathway

Notch信号途径对小鼠骨髓单核来源树突状细胞和巨噬细胞分化发育的调控

Notch signaling pathway is an evolutionarily highly conserved mechanism for cell-cell communication , which controls differentiation and proliferation , and plays an important role in embryogenesis and many types of cell fate determination .

Notch信号是一个在进化中高度保守的反映细胞间通讯机制的通路，它调控细胞的分化和增殖，在胚胎发育和细胞命运的决定中发挥重要的作用。

Studies found that Notch signaling pathway is closely linked to cell differentiation , proliferation , apoptosis , adhesion and epidermal cells to mesenchymal transition and it is essential for the normal development of most organizations .

研究发现，Notch信号通路与细胞的分化、增殖、凋亡、粘附及表皮细胞向间质转化有密切联系，对大多数组织的正常发育至关重要。

The precise regulation of the Notch signaling pathway is essential for the normal development of most organizations . Aberrant regulation of Notch signaling leads to abnormal tissue development and the occurrence of tumors and other diseases .

Notch信号途径的精确调控，对大多数组织的正常发育至关重要；其异常凋控引起组织发育异常，并导致肿瘤等多种疾病的发生。

In the process of embryonic vascular development , Notch signaling pathway plays a key role in maintaining the normal structure and function of embryonic vascular network by regulating the arteriovenous differentiation and endothelial Tip cell and Stalk cell specification .

在胚胎血管发育过程中，Notch信号通路调控着动静脉血管的分化和血管内皮Tip细胞和Stalk细胞的命运选择，对胚胎血管网络正常结构和功能的维持起到了关键作用。

The anti-tumor effect of docetaxel is reflected in the regulation of proliferation and apoptosis of tumor cells through multiple signaling pathways . Whether docetaxel has cross-talk with the Notch signaling pathway has not been reported .

多西他赛的抗肿瘤效果即体现在其通过对多个信号通路的调控影响肿瘤细胞的增殖和凋亡，其与Notch信号通路是否存在交叉传导，目前为止未见文献报道。

Notch signaling pathway has an important role in the development of multi-tissue and multi-organ , especially in the regulation of the nervous system development in animals while RBP-J κ is a key molecular in the Notch signaling pathway .

Notch信号途径参与动物多种组织和器官尤其是神经系统的发育调节。

Notch isa classic signaling pathway , its family members are highly conserved in structure .

Notch信号通路是一种经典的信号通路，该通路的家族成员在结构上具有高度的保守性。